Events and Barriers are opportunities to address potential failure points with targeted Therapy Support for patients and clinicians.


KEY EVENTS

Open All Events
Diagnosis
  • Patient identification and diagnosis
  • Clinician recommendation of cell & gene therapy
Treatment Initiation
  • Patient decision to move forward
  • Reimbursement
  • Harvesting visit
Ongoing Treatment
  • Shipment of harvested cells
  • Shipment of therapy
  • Patient return for therapy infusion
  • Onset of side effects (possible)
  • Onset of efficacy (possible)
  • Patient return for monitoring visits
  • Ongoing data/evidence collection for payers

FOCUS AREA

Cell & Gene Therapies

 

Events and Barriers are opportunities to address potential failure points with targeted Therapy Support for patients and clinicians.


KEY EVENTS

Open All Events
Diagnosis
  • Patient identification and diagnosis
  • Clinician recommendation of cell & gene therapy
Treatment Initiation
  • Patient decision to move forward
  • Reimbursement
  • Harvesting visit
Ongoing Treatment
  • Shipment of harvested cells
  • Shipment of therapy
  • Patient return for therapy infusion
  • Onset of side effects (possible)
  • Onset of efficacy (possible)
  • Patient return for monitoring visits
  • Ongoing data/evidence collection for payers

BARRIER ANALYSIS

Open All Barriers
PATIENT
BARRIERS
Understanding condition/treatment

    Unclear risk-benefit ratio

Financial/cost issues

    Cost burden of office visits and treatment

    Impact of disease and treatment on work

Clinician–patient relationship

    Effective communication, trust, etc

    Clinician experience; those new to cell & gene therapies may worry patients

Therapy logistics

    Logistics of harvesting/infusion visits

    Logistics of monitoring visits

Psychosocial/emotional issues

    Shock at diagnosis/disease progression

    Doubts/fear at treatment decision due to unknowns

    Anxiety/depression

    Worries about disease progression aggressiveness

Motivation/treatment fatigue

    Management of side effects/other treatment complexities

    Ongoing value assessments for payers

CLINICIAN
BARRIERS
Limited time/resources

    Lack of understanding of cell & gene therapies

    Lack of confidence in ability to handle cell & gene therapies

    Integration of cell and gene therapies into office responsibilities

Financial/cost issues

    Concerns about reimbursement

Therapy logistics

    Coordination of harvested cell shipments

    Management of cold-chain

Patient communication/expectation setting

    Identification/management of safety/side effects

Ongoing disease and treatment monitoring

    Patient returning for harvesting/infusion/follow-up visits

    Data/evidence collection (eg, quality of life, efficacy measures) at and between follow-up patient visits

HCS
SOLUTION

A comprehensive program that engages patients to understand their condition and cell & gene therapy, set expectations, prepare and stay motivated for therapy, and overcome other barriers by working to:

  • Support initial visit to harvest cells
  • Coordinate harvested cell shipments and cold-chain cell & gene therapy
  • Ensure patients attend scheduled visits
  • Support patients to manage side effects/other complexities of therapy
  • Ensure necessary payer reporting for pay for value schemes
  • Manage data/evidence collection (eg, quality of life, efficacy measures) between follow-up visits, including reporting to provider/payer/pharma